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Medication safety

Medicines you shouldn't stop suddenly

Running out of most medicines for a day isn't dangerous. For some, it can be. Know which of yours are on this list.

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Short answer: Some medicines can cause rebound or withdrawal problems if stopped abruptly, including beta-blockers such as metoprolol, clonidine, antidepressants, seizure medicines, long-term steroids, insulin and blood thinners. If you're about to run out, call your pharmacy about an emergency supply and contact a prescriber; in Florida, a $39 telehealth review can help for established, non-controlled medicines.

Medicines that need a plan

  • Beta-blockers (metoprolol, atenolol, carvedilol, propranolol): rebound high blood pressure, chest pain, rhythm problems
  • Clonidine: a sharp rebound rise in blood pressure
  • Antidepressants (SSRIs, venlafaxine, duloxetine): dizziness, irritability, flu-like discontinuation symptoms
  • Seizure medicines: breakthrough seizures
  • Long-term steroids such as prednisone: the body may not make enough of its own cortisol
  • Insulin: in type 1 diabetes, diabetic ketoacidosis can develop quickly
  • Blood thinners: higher risk of clots or stroke
  • Gabapentin and pregabalin: withdrawal and, rarely, seizures
  • Controlled medicines such as benzodiazepines and opioids: dangerous withdrawal. We don't prescribe these; contact your prescriber

If you're about to run out

  1. Call your pharmacy. Florida pharmacists may give a one-time emergency supply of up to 72 hours (Fla. Stat. §465.0275)
  2. Contact your prescriber's office or on-call line
  3. For established, non-controlled medicines, request a $39 refill review if you're physically in Florida
  4. Don't double up when you restart, and ask a pharmacist how to resume

When to get emergency care

Chest pain, a seizure, very high blood pressure with headache or confusion, severe vomiting with high blood sugar, or thoughts of self-harm: call 911 (or 988 for a mental health crisis).

Common questions

Is it dangerous to miss one day of blood pressure medicine?

For most blood pressure medicines, a missed day isn't dangerous, but beta-blockers and clonidine are exceptions. Don't let it stretch on; get a refill arranged.

Can you refill insulin?

Insulin needs a closer look. Text us before paying. If you have type 1 diabetes and are out of insulin, treat it as urgent: call your pharmacy about an emergency supply and contact a clinician right away.

Can you refill my benzodiazepine or pain medicine?

No. We don't prescribe controlled substances. Stopping them suddenly can be dangerous, so contact your prescriber or seek in-person care.

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